What Are DigeZyme® Digestive Enzymes and What Are Their Benefits?

Did you know that digestive health determines the well-being of the individual, because controlling this complex system can help improve everyone's health, mood and happiness?

If the digestive system is not functioning as it should, many health problems, such as poor absorption of nutrients, weight problems, nausea, bloating, constipation, stomach pain and diarrhea, and even more complicated conditions such as acid reflux disease or irritable bowel syndrome.

There are several known factors that influence the health of the digestive system, i.e. inadequate lifestyle and dietary habits, stress, age, genetic factors, food additives and chemicals as well as a lack of physical activity.

In today 's rapidly changing world, modern lifestyle and eating habits cause many inconveniences associated with the digestive system that has been most affected, leading to changes in digestive enzyme activity and their insufficiency.

Enzymes can be described as simple proteins present in every living cell, where they act as "biological catalysts" for the regulation of various biological reactions, including digestion. Some digestive enzymes are involved in breaking down proteins, carbohydrates and fats and other complex molecules in foods. By doing so, they facilitate the digestive process and thus help the body to better absorb nutrients.

However, in some individuals, due to ageing or vice versa, the body's natural ability to produce certain pancreatic enzymes, such as lipase, amylase, and other additional pancreatic enzymes that play an important role in macronutrient digestion, begins to decline with age.

Thus, deficiency of normal digestive function associated with enzyme deficiency can lead to malabsorption and many related health problems if enzyme deficiency remains unchanged.

Fortunately, it is possible to compensate for the lack of enzymes with enzyme supplements, which are very important in today's world.

What are Gastrointestinal Digesters?

Digestive enzymes can be divided into several categories according to which substrates they can bind to and degrade. Proteins are broken down by proteases and peptidases, fats and fatty acid chains are broken down by lipases, and carbohydrates, starches and sugars are broken down by amylases, whereas the simplest nucleic acids and nucleotides are broken down by nucleases. Although all of these enzymes are produced in the human body, their site of action can vary greatly - some of them work only in the mouth, while others act in the stomach, intestine or pancreas.

What is DigeZyme®?

DigeZyme®, also known as digestive enzymes, is a specially selected key 5 enzymes that, when ingested, help break down macromolecules into smaller building blocks, such as amino acids. By breaking down molecules such as proteins, lipids, etc., enzymes help the body absorb the amino acids and other nutrients it needs in a faster and more efficient way.

The action of DigeZyme® is based on targeting specific substrates or chemicals involved in chemical reactions with the product. Simply put, these enzymes target substances that are degradable or otherwise modified.

What is the result? The remedy eliminates toxins accumulated in the body, maintains a normal function of the digestive system, improves the quality of sleep, maintains a normal state of mental health, helps maintain a constant body weight, helps maintain a healthy and smooth skin. It also helps to neutralize the toxins in the body accumulated from undigested food; maintains a normal digestive function; maintains a normal immune function; helps maintain a normal body weight.

What Enzymes Are Included in DigeZyme®?

Amylase. It breaks down carbohydrates such as starches and glycogen and polysaccharides into smaller molecules;

Cellulase. It breaks down cellulose and chitin; helps to assimilate the nutrients found in fruits and vegetables;

Lipase. It breaks down fat molecules and accelerates the metabolism of fat; helps maintain a normal function in gallbladder;

Protease. It breaks down proteins and helps maintain the immune system;

Lactase. It breaks down lactose (milk sugar) and is useful for people who are lactose intolerant.

Properties of Amylase

Amylase is a dextrinogenic enzyme that is classified to the type of alpha amylases that converts starch into dextrin. Starch is naturally heterogeneous and consists of two polysaccharide molecules, amylose and amylopectin.

Structure of Amylose

The amylose molecule consists of long, straight glucose chains linked by alpha-1.4 bonds.

Structure of Amylopectin

Amylopectin is a branching, shrub-like molecule composed of glucose particles linked by alpha-1.6 bonds at the branching sites.

Amylase (a type of alpha-amylase) acts on the alpha-1.4 intermolecular linkages in the amylose molecule and the amylopectin molecule, respectively, to form alpha-maltose and release low molecular weight alpha-dextrins.

• The effect of pH: the amylase molecule remains stable at pH 5.0 to 7.0 with an efficiency of 75-100%;
• The temperature effect: maximum efficiency is achieved at 55 ° - 60 ° C

For longer periods of action, the optimum temperature for the enzyme does not exceed 37 degrees. Studies have shown that when heated for one hour at pH 7, the enzyme in DigeZyme remains stable below 40 degrees Celsius, whereas at 50 degrees Celsius the activity of the enzyme decreases to 20%.

The Properties of Proteases

Depending on the pH level, microbial prostheses are divided into:

Alkaline proteases

Active at pH between 7.0 and 11.0

Neutral proteases

Active at pH 6.0-9.0

Acidic proteases

Active at pH between 2.5 and 4.0

The neutral protease contained in DigeZyme® remains stable at pH between 6.0 and 8.0. This enzyme has a broad spectrum of activity and can digest more than one protein molecule in food. The activity of this enzyme is somewhat similar to that of proteolytic gut enzymes, which are most active at neutral and alkaline pH.
These enzymes help to break down polypeptides into peptides and amino acids.
The properties of the proteases contained in DigeZyme® were determined using the milk protein casein as a substrate. The results showed that the protease contained in this enzyme complex is neutral and most active at pH 6.0-8.0.

• Lactase catalyzes the conversion of beta-D-galactose to lactose.
• Lipase. By using olive oil as a substrate, the lipase in DigeZyme® was found to be most active at pH 7.0.
• Cellulase. The activity of an enzyme is determined by measuring the amount of sugar released from sodium salts in carboxymethylcellulose. The cellulose in DigeZyme® is most active in the pH range from 4.0 to 4.5.

What is the Origin of DigeZyme® Digestive Enzymes?

Commercial digestive enzymes are isolated from a variety of sources such as the pancreas of higher animals (pigs or cattle), vegetables or cereals such as barley, and microorganisms such as bacteria and fungi.

The multi-enzyme complex DigeZyme® contains a wide range of effective enzymes produced during the fermentation process.

• Alpha-amylase / Fungus / Aspergillus oryzae
• Lactase / Fungus / Aspergillus oryzae
• Lipase / Fungus / Rhyzopus oryzae
• Cellulase / Fungus / Trichoderma longibrachiatum
• Neutral protease / Bacterial / Bacillus licheniformis
• Acidic protease / Fungus / Aspergillus oryzae

Effects of DigeZyme® on athletes and those with frequent muscle aches

Delayed Onset of Muscle Soreness (abbr. DOMS), a specific type of muscle pain, is a widely studied phenomenon, often occurring after intense training that is not preceded by a warm-up. Muscle spasms, passive tightening, swelling, loss of strength and endurance, and local pain are the symptoms that usually occur within 24 hours of training and last for 3-4 days.

To date, many studies have been conducted to analyze DOMS, but none have answered the question of how to prevent or treat DOMS. Medications such as ibuprofen are most often used to relieve pain, but in fact, they can only prolong the healing process of the muscles and cause other side effects.

However, scientists believe that it may be beneficial to use digestive enzyme supplements other than DOMS to relieve symptoms. Sitosterols, plant sterols, and protease enzymes are known to help reduce DOMS-related pain and inflammation. Oral denture supplements can also help the body to recover from various injuries or traumas.

A relatively recent study aimed to measure the effectiveness of DigeZyme® in reducing delayed muscle pain.  The study involved 20 male volunteers given placebo or multienzyme complex supplements three times daily. The investigation lasted three days.

The results showed that DigeZyme® reduced the muscle discomfort and unpleasant feelings experienced by individuals after intense training. It has also been observed that the levels of biomarkers that signal about inflammation have been reduced in those taking digestive enzymes.

Symptoms of Digestive Enzyme Deficiency

The most common and easily recognizable symptom of poor digestive enzyme activity is the absence or weak effect of the enzyme lactase, which breaks down milk sugar (lactose) into easily absorbed simple sugars. In the case of an absence or a lack of this enzyme, milk sugar travels through the digestive tract untreated all the way to the large intestine, where it begins to ferment the bacteria that are present there. Excessive fermentation manifests itself as symptoms of gas accumulation and diarrhea - those are typical complaints of individuals intolerant to lectosis.

The pancreas is an organ of the digestive system that produces several enzymes that include three major groups of enzymes: amylase, protease and lipase. A healthy pancreas releases these enzymes daily into the small intestine, where food is turned into beneficial substances for the body. The development of some pancreatic diseases or other disorders, such as those caused by excessive alcohol consumption, also significantly reduces the amount of enzymes released by the pancreas, which leads to poor digestion.

Another disease that can disrupt the normal digestive process is gastritis, otherwise known as gastric wall inflammation. The mucous membrane of the stomach is made up of specific cells that produce pepsine, i.e. an enzyme that breaks down stomach acids, mucus and proteins. Generally speaking, any inflammatory process in the gastrointestinal tract directly affects the release of enzymes and the inhibition of the activity of specific cells that secrete them.
Paradoxically, a lack of enzymes in the body naturally causes a mild inflammation of the intestine, which further slows down the production of enzymes. In such cases, the use of digestive enzyme supplements becomes perhaps the main tool that can help to restore the normal functioning of the intestine and the digestive system.

Symptoms of Gastrointestinal Disorders

Some of the most noticeable signs of a malfunctioning of the digestive system are flatulence, bloating, nausea, abdominal pain, diarrhea or constipation.
Insufficiently digested nutrients cannot pass through the intestine-blood barrier, making them inaccessible to metabolic processes in specialized tissues and organs of the body.

A chronic deficiency of digestive enzymes can result in a lack of nutrients in the body and can lead to weight gain due to increased accumulation of fats. The frequently neglected deficiency of digestive enzymes in the body can eventually lead to the development of chronic degenerative and inflammatory processes or even the development of neoplastic diseases.

Why Supplement Your Diet With Digestive Enzyme Supplements?

In order to improve your overall body function, it is important to take into account the frequent digestive problems that may be indicative of an apparent lack of digestive enzymes.

Restoring the sufficient level of enzymes should be a priority, not only willing to finally get rid of the frequent digestive problems, but also seeking to guard against more dangerous, long-term illnesses. Having restored the amount of digestive enzymes that are effective in the body allows the body to absorb more of the vital nutrients, vitamins and minerals.

Ideally, normal levels of digestive enzymes in the body should be maintained through proper nourishment and the promotion of an active and healthy lifestyle, but in reality, recovery of the damage caused by dietary calories often requires an additional "kicking". The body often needs additional help due to naturally occurring aging processes.

The use of digestive enzyme supplements to balance the digestive system is primarily recommended for people suffering from digestive system disorders (such as gas accumulation, constipation, diarrhea, spasmodic pain) and as a protective measure for middle-aged and elderly people.

The Need for Additional Digestive Enzymes

Digestive enzyme supplements are recommended for individuals suffering from body stress due to sudden changes in diet, constant exposure to contaminants in the environment, as well as air changes or frequent travelling.

It is also recommended to recent surgery patients taking antibiotics or immune suppressants.

Digestive enzyme deficiency can also be caused by pancreatic lesions, various diseases and injuries.

Some individuals suffer from malfunctioning of the system of specific digestive enzymes due to the genetic factors leading to digestive and metabolic disorders such as lactose intolerance.

Studies of Toxicity

The reverse bacterial cell mutation test in DigeZyme® supplements was performed using the Salmonella typhimurium test scores TA98, TA100, TA1535 and TA1537.

The test was negative and DigeZyme® was approved as a non-mutagenic agent.

What are the Benefits of DigeZyme®?

DigeZyme® is a very useful preparation because of its high content of amylases, lactase, cellulose, lipases and prostheses. All these substances have only their intrinsic useful properties and specific characteristics.

DigeZyme® helps to reduce the amount of toxins accumulated in the body through the consumption of poorly digestible foods or the inability of the body to break down specific macromolecules and micromolecules. DigeZyme® also improves the overall digestive system performance by speeding up the digestion process with these enzymes. In the latter process, the body is provided with the simplest and most readily absorbed forms of amino acids to assist normal protein synthesis, cognitive function, and immune function.

So Why Choose DigeZyme®?

In fact, it's quite simple. Although most foods contain relatively high levels of digestive enzymes, this does not mean that they are all fully absorbed. According to scientific research, at about 48 degrees Celsius, enzymes are denatured, which means that very little or no enzymes remain in the foodstuffs that have undergone heat treatment and eventually eating such foods.

This is why it is worth taking DigeZyme® nutritional supplements to help your body absorb more digestive enzymes. It also increases the response of the body's immune system to harmful environmental factors, increases nutrient uptake and accelerates the processes of muscle fibers and regeneration of cells.
Although DigeZyme® is still a relatively new product, its effects on the gastrointestinal tract have been proven. This supplement is recommended for people who want to take in as much nutrients as possible or recover from intense workouts.

How to Take Enzymes?

DigeZyme® can be taken in a variety of forms, including protein-enriched nutritious cocktails and all-in-one powders. It can also be used in carbohydrate and protein based restorative products. The daily intake of powder mixes and capsules is 150 mg of DigeZyme® complex. It is recommended to take 50 mg three times a day. Each capsule of the BIYOMA Digestive Complex contains exactly 50 mg of DigeZyme® enzymes, making it very convenient and easy to take - 1 capsule with food, up to 3 times daily.

If you have a specific disease, or are taking additional medicine or supplements, be sure to consult your doctor or pharmacist before starting to take any new supplements. The information contained herein should not be construed as a recommendation for treatment or any other health issues. We encourage you to make personal health decisions individually, based on an evaluation of a variety of information sources.